| CAS No.: | 443-48-1 |
|---|---|
| Packaging Material: | 25kg/Drum |
| Storage Method: | Dry and Cool Place |
| Shelf Life: | 24months |
| Nutrient Composition: | Protein |
| Resource: | Natural |
| Samples: |
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| Customization: |
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| Name of product: | Metronidazole | |
| Expiry Date: | 4 years | |
| ITEMS | STANDARDS | RESULTS |
| Characteristics | a white or yellowish crystalline powder, slighting sobube in water, in acetone, in alcohol and in methylene, chloride, very slightly solube in ether | COMPLY |
| Identification | a) Melting point 159-163ºC | 161.1-161.3ºC |
| b) Specific absorbance 365-395 | b) 375 | |
| c) IR | c) COMPLY | |
| d) The solution gives the reaction of primary aromatic amines | d) COMPLY | |
| Appearance of solution | SUSPENSION | COMPLY |
| AND SOLUTION GY6 | ||
| Related substances | Impurity:0.1MAX | 0.02% |
| Total impurity:0.2MAX | 0.06% | |
| Heavy Metal | 20PPM MAX | <20PPM |
| Loss on drying | 0.5% MAX | 0.19% |
| Particle size | 40-80mesh | COMPLY |
| Assay | 99.0%-101.0% | 99.4% |
Pharmacology
In addition to anti-trichomonas and anti-amoeba, in recent years, widely used in anti-anaerobic infections. This product nitro, anaerobic environment in the reduction of amino and anti-anaerobic bacteria show the role of aerobic bacteria or facultative aerobic bacteria is invalid. The following anaerobic bacteria have good antibacterial effect: Bacteroides, including Bacteroides fragilis; Fusobacterium; Clostridium, including tetanus; partial eubacteria; digestive bacteria and digestion Streptococcus and so on. Oral absorption of good (> 80%), oral 250mg or 500mg, 1 ~ 2 hours serum drug concentration peak, respectively 6μg / ml and 12μg / ml. Intravenous infusion of the goods 15mg / kg, after every 6 hours infusion of 7.5mg / kg, plasma drug concentration reached a peak concentration of 25μg / ml, trough concentration of up to 18μg / ml. This product is widely distributed in the body, can enter the saliva, milk, liver abscess pus, can also enter the cerebrospinal fluid (normal CSF concentration of up to 50% of blood). In the body, the side chain oxidation or metabolism with glucuronic acid binding, 20% of the drug is not metabolized. Its metabolites also have a certain activity. Metronidazole and its metabolites by a large umber of urinary excretion (60% of the total ~ 80%), a small amount of excretion from the feces (6% ~ 15%). T1 / 2 is about 8 hours.
Indications
Mainly for the treatment or prevention of anaerobic bacteria caused by the system or local infection, such as the abdominal cavity, digestive tract, female genital tract, lower respiratory tract, skin and soft tissue, bone and joint parts of anaerobic infections, sepsis, Membranitis, meningeal infection and the use of antibiotics caused by colitis is also effective. Treatment of tetanus and tetanus antitoxin (TAT) in combination. Can also be used for oral anaerobic infections.
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A: Please provide the exact or approximate quantity, packing details, destination port or special requirements, then we could give you the price accordingly.
Q2: What is your terms of payment?
A: TT Transfer, CAD, L/C, All is available.
Q3: How can I get a sample?
A: We can provide free samples for your test.
Q4: Do you have MOQ ?
A: Yes, but low MOQ for sample checking is available.
Q5: How do you garantee the quality?
A: First of all, our quality control will reduce the quality problem to near zero. When the production is finished, they'll take samples from every batch of cargo, and send to our lab for inspection. After passed the inspection, then we will arrange the delivery.
Q6: How about your after-sale service ?
A: If any technical or quality problem after you receive the cargo, you can contact us any time. If the problem caused by us, we will send you free goods for replacement or refund your loss.
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